MediQuest Society

Intermittent fasting triggers surprising changes in the brain

Losing weight may involve rewiring the gut and the brain at the same time. In a study of obese adults, an intermittent fasting-style diet led to significant weight loss, healthier metabolic markers, and notable shifts in gut bacteria. Brain scans also revealed changes in regions tied to appetite, cravings, and self-control. The results suggest the gut microbiome and brain may work together to influence weight-loss success.

More than one billion people worldwide now live with obesity, a condition that raises the risk of cardiovascular disease, diabetes, and several types of cancer. Yet losing weight and keeping it off can be extremely difficult. The body does not simply respond to fewer calories in a straightforward way. Signals from the gut, hormones, metabolism, and the brain can all influence hunger, cravings, and weight regain.

One approach that has drawn growing interest is intermittent energy…

Why cancer spreads more in middle age than in old age

Melanoma may not become steadily more dangerous with age as scientists once assumed. In a surprising discovery, researchers found that cancer spread was lowest in young mice, surged in middle-aged mice, and then dropped again in very old mice. The key appears to be a special type of immune cell that helps keep cancer dormant and prevents it from spreading.

Cancer becomes more common with age and is often harder to treat in older adults. Yet most cancer studies in mice do not reflect that reality. Fewer than 10% of mouse experiments use aged animals, with researchers typically relying on mice that roughly correspond to humans in their early 20s.

That gap may help explain why many cancer therapies that perform well in laboratory studies ultimately fail in human clinical trials.

New findings from Fox Chase Cancer Center, presented…

Doing this throughout life may cut Alzheimer’s risk by 38%

A lifetime of mental stimulation—like reading, writing, and learning new skills—may help protect the brain as we age. People with the highest levels of cognitive enrichment had a much lower risk of Alzheimer’s and experienced symptoms years later than those with the lowest levels.

Engaging in mentally stimulating activities across your lifetime, including reading, writing, and learning new languages, may be linked to a lower risk of Alzheimer's disease and slower cognitive decline. That is the conclusion of a study published recently in Neurology, the medical journal of the American Academy of Neurology. Researchers emphasize that the findings show an association, not proof that lifelong learning directly prevents Alzheimer's.

The study found that people who stayed more intellectually engaged throughout their lives developed Alzheimer's disease about five years later than those with the lowest levels of mental stimulation. They also…

Scientists say this simple music trick can boost workout endurance by 20%

A new study shows that listening to your own favorite workout music can dramatically boost endurance. Cyclists exercising with self-selected songs lasted nearly 20% longer than when riding in silence, yet they didn’t feel more exhausted at the end. Researchers say music may help people stay in the “pain zone” longer without increasing perceived strain.

The study focused on recreationally active adults cycling at high intensity while listening to music they personally chose. Most of the tracks fell within a tempo range of about 120-140 beats per minute. Compared to exercising in silence, participants were able to continue riding for nearly six additional minutes before reaching exhaustion.

endurance by nearly 20 %, highlighting a simple strategy that may benefit both athletes and casual exercisers.

The study focused on recreationally active adults cycling at high intensity while listening to…